“A guy walks into a bar…” is a typical form of what has been called the “bar joke.” A version with COVID-19 (coronavirus) variants is:
       
“Alpha, Delta, and Omicron walk into a bar and order a few Coronas. ‘That’ll be $20.21,’ the bartender says.”
     
The variants happened in the year 2021. The joke was posted on Twitter by Tezcatlipoca Telos on December 6, 2021, and on Reddit—Dadjokes on December 7, 2021.
   
     
Wikipedia: COVID-19 pandemic
The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in December 2019 in Wuhan, China. The outbreak was declared a Public Health Emergency of International Concern in January 2020 and a pandemic in March 2020.
   
Twitter
Tezcatlipoca Telos
@sharonafinlay
Alpha, Delta, and Omicron walk into a bar, order a few Coronas, and the bartender replies, “That’ll be 20.21.”
11:10 PM · Dec 6, 2021·Twitter for iPhone
 
Reddit—Dadjokes
Posted by u/YoviQ December 7, 2021
Alpha, Delta, and Omicron walk into a bar and order a few Coronas.
“That’ll be $20.21”, the bartender says.
COMMENTS
Delicious-Duck1782
It was more than a few. I heard they closed the bar down
 
Twitter
Bob Kostic
@causticbob
Alpha, Delta, and Omicron walk into a bar and order some Coronas.
“That’ll be $20.21,” the bartender says.
5:51 PM · Dec 7, 2021·Twitter Web App
 
Twitter
Joe Sacher
@sacherjj
Alpha, Delta, and Omicron walk into a bar and order a few Coronas.
The bartender said “That’ll be $20.21”.
9:03 PM · Dec 7, 2021·Twitter Web App