“Hustle Town” (or “Hustletown”) is a nickname for the city of Houston. There was a night club (ca. 2000) called Hustle Town in Houston. The nickname “Hustle Town” is one of several Houston nicknames used in hip-hop, including “H-Town” and “Screwston.”
 
South Park Mexican (Carlos Coy) released an album called Hustle Town in 1998, and he either invented or (at least) popularized the nickname.
 
   
Urban Dictionary
h-town
H-Town(AKA Hustle Town, AKA Houston) is where all the best Rappers come from.
Somebody:Hey yo Flip whatchu reppin?
Lil Flip:H-Town nigga.
by Devilish Eminem Jun 18, 2003
     
Wikipedia: South Park Mexican
Carlos Coy (born on October 5, 1970 in Houston, Texas) better known by his stage name South Park Mexican is a rapper, currently incarcerated for child molestation. His stage name derives from the South Park neighborhood in which he was raised in part of his life. 
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Dope House Records albums
In 1995, Carlos, along with his brother Arthur, Jr., founded his own record label, Dope House Records [3]. He later released his second album, Hustle Town, through his label with distribution in Houston under Southwest Wholesale. In 2000 he signed a joint venture between his label and Universal Music Group which earned him a $500,000 advance and national distribution.[3] [4] In total he has released nine albums.
 
Discography
Hillwood (1992)
Hustle Town (1995) ...
       
cdbaby.com
South Park Mexican
Hustle Town
© 1997 Mary Jane Publishing Inc.
SPM’s second solo album. Hustle Town was named after his city, Hustle Town AKA Houston.
   
NOTES
SPM’s second solo album. Hustle Town was named after the city SPM was born in, Hustletown AKA Houston. The album features popular hit track “Mary-Go-Round”, which later became a theme song at the SPM concerts.
 
Other featured hits include Streets on Beats and Block of Rock. His lyrical & witty writing skills began to catch the attention of audiences across the region, but it wasn’t until the production of this album that SPM began producing his own instrumentals. Still young & fresh in the rap game, SPM again brings hardcore rap to the table with fresh beats to accompany them. Hustle Town remains one of Dope House Records best selling album. 
   
Amazon.com
Hustle Town
South Park Mexican  
Audio CD (March 3, 1998)
Original Release Date: March 17, 1998
Label: Dope House  
 
South Park Mexican Lyrics
“Hustle Town”
[SPM talking]
Eh he he he he
Hustle Town my city maan!
Born and raised baby
Yo I dedicate this jam to all the single mothers
Raisin’ men in a big city
I know it’s hard
Let ‘em know what’s up Filero
(...)
[Chorus: SPM]
Hustle Town Hustle Town
The city of dreams
Where we creep through the hood
And we serve them dope fiends
Hustle Town
The shit don’t stop
Roll rental cars
And we keep the glock cocked
 
Google Groups: rec.music.hip-hop
Newsgroups: rec.music.hip-hop, alt.music.gangsta.rap
From: .(JavaScript must be enabled to view this email address) (OverTiME the Beyonder)
Date: 1999/03/23
Subject: From the Mind of OverTiME- The EPITAPH Spring’99  
 
South Park Mexican- Hustletown  
   
Google Groups: alt.music.gangsta.rap
Newsgroups: alt.music.gangsta.rap
From: .(JavaScript must be enabled to view this email address) (£ø§† $øÜ£)
Date: 1999/06/09
Subject: Re: To Og STYLE
 
hell yeah, Hustle town tight, i got that cd and Power Moves.  my fav song in power moves is “the 4gotten verse” screwed up, and in hustle town, its run away screwed, and mary go round.
 
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From: “Philip”
Date: Sat, 11 Nov 2000 00:46:47 -0600
Local: Sat, Nov 11 2000 1:46 am
Subject: Streets On Beats
 
I move a hundred pounds in my hustle town come around, fuck ‘em down with my underground. Puffin pow-wow clouds in my tee-pee wit’ my hiena hollerin’ “release me”, prime time like shines on the mines, hellafied rhymes, uh, you ben won 25 times. Another fool puttin’ down da truf’ you can’t fuck witf’ tha riddla on da roof. Mister go-getta’ kick the mo betta’ if she wanna go….fuck the ho let her.
The wanderer, Hillwood Hustla’ turn your back on your gal and UH!, straight clown in my H-Town is you hoes really ready take down, break down? 
 
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From: Rodrigo

Date: Sun, 17 Feb 2002 16:58:10 -0600
Local: Sun, Feb 17 2002 5:58 pm
Subject: Re: I am new…wonderin where every1 is reppin
   
Reppin Houston, 20 inch subs on 20 inch dubs
Screwston, H Town, Hustle Town, whatever…
   
Austin Chronicle (September 5, 2003)
Fresh, who’s worked at 3rd Coast about a month, says it’s the slo-mo, syrup-fed sounds of Houston (aka “Screwston,” “Hustle Town”) that rev his customers’ engines.
Amber’s space
May 16, 2006
TEXAS VS CALI!
(...)
Hustle Town, h-town, screwston!