A plaque remaining from the Big Apple Night Club at West 135th Street and Seventh Avenue in Harlem.

Above, a 1934 plaque from the Big Apple Night Club at West 135th Street and Seventh Avenue in Harlem. Discarded as trash in 2006. Now a Popeyes fast food restaurant on Google Maps.

Recent entries:
“The Milky Way is a hard place to be if you’re galactose-intolerant” (6/5)
“Since nobody reads the 5,000 page bills. let’s slip in ‘term limits‘“ (6/5)
“Since nobody reads the 5,592 page bills, let’s slip in ‘term limits‘“ (6/5)
“I’m moving from the Milky Way to the Soymilky Way galaxy. I’m galactose intolerant” (6/5)
Entry in progress—BP (6/5)
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Entry from November 24, 2013
Statin Island (statin + Staten Island)

"Staten Island” is often misspelled as “Statin Island.” Staten Island has no special connection to statins, which are drugs used to lower cholesterol.

There have been many “Statin Island” puns in the 2000s. “The best place in New York City to lower cholesterol is Statin Island” was posted on Twitter on September 25, 2012.

Wikipedia: Statin
Statins (or HMG-CoA reductase inhibitors) are a class of drugs used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. Increased cholesterol levels have been associated with cardiovascular disease, and statins have been found to prevent cardiovascular disease in those who are at high risk.

Wikipedia: Staten Island
Staten Island /ˌstætən ˈaɪlənd/ is one of the five boroughs of New York City, in the U.S. state of New York, located in the southwest part of the city. Staten Island is separated from New Jersey by the Arthur Kill and the Kill Van Kull, and from the rest of New York by New York Bay. With a population of 468,730, Staten Island is the least populated of the boroughs but is the third-largest in area at 59 sq mi (153 km2).

Google News Archive
29 August 2001, Manila (Philippines) Standard, pg. 7A, col. 2:
Generally speaking, these drugs have saved many lives and are collectively known as Statins because they were first synthesized on Statin Island.

“Statin” Island: Muscle Pain, Digestive Distress & Liver Damage?
Ben Fuchs
April 26, 2011
Statin drugs are among the best selling drugs in the world. They were initially approved by the FDA for lowering the cholesterol of patients who had a history of heart problems. Today their use for “off label indications,” conditions the drug was not originally approved for, are skyrocketing – and statins are used as cholesterol-lowering drugs for just about everyone.

I heard Pfizer is opening a new manufacturing plant in the Pacific for cholesterol lowering drugs, they’re calling it Statin Island.
7:18 AM - 19 Jun 11

The Caribbean
Staten Island has so many people on cholesterol lowering drugs it’s been nicknamed “Statin Island.”
10:16 AM - 26 Mar 12

Psychology Today
A Statin Island of Woe: Are Depression and Cholesterol-lowering Connected?
Are statin drugs bringing you down?

Published on August 20, 2012 by Peter Bongiorno, ND, LAc in Inner Source
Cholesterol-lowering statin medications are the number one money-making medication.

Edward Philips
The best place in New York City to lower cholesterol is Statin Island.
3:42 AM - 25 Sep 12

Posted by Barry Popik
New York CityNeighborhoods • Sunday, November 24, 2013 • Permalink