"Waxination” or “waxxination” are variant spellings of “vaccinate,” sometimes for jocular effect and sometimes to get around computer algorithms. The spellings became popular in 2020 with the COVID-19 (coronavirus) pandemic, but were used earlier.

“Waccine” (wack + vaccine), “waccinate,” “waccination,” “waxxine” and “waxinate" or “waxxinate” or “waxxxinate” are similar terms.

Wikipedia: COVID-19 pandemic
The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in December 2019 in Wuhan, China. The outbreak was declared a Public Health Emergency of International Concern in January 2020 and a pandemic in March 2020.