A request to “pick up” an item from the store means to get it from the store. It does not mean to literally pick up the item, but there are jokes. This was posted on Twitter by “brandAn is good” on October 22, 2016:
   
Wife: can you pick up milk?
Me: [lifts gallon] yea it’s easy
Wife: I mean from the store
Me: I would imagine it weighs the same there too
 
 
Twitter
brandAn is good
@LeBearGirdle
Wife: can you pick up milk?
Me: [lifts gallon] yea it’s easy
Wife: I mean from the store
Me: I would imagine it weighs the same there too
3:50 PM · Oct 22, 2016·Twitter for Android
     
Twitter
Danger
@Schmidtyy
Mom: Can you pick up milk?
Me: [lifts gallon] yea it’s easy
Mom: I mean from the store
Me: I would imagine it weighs the same there too
8:31 AM · Oct 23, 2016 from Melville, IL·Twitter for Android
   
Reddit—Jokes
Posted by u/theconfuserx2 January 18, 2017
Wife: “Can you pick up milk?”
Me: lifts gallon
“Yeah, it’s easy.”
Wife: “I mean from the store.”
Me: “I’d imagine it weighs the same there too”
 
Twitter
ren
@hallofegress
tony: can you pick up milk?
steve: yeah, it’s pretty easy
tony: I meant from the store
steve: I would imagine it weighs the same there too
7:51 PM · May 25, 2017·Twitter for Android
   
Twitter
Chief DADDY the Data Analyst
@David__Edu
Wife: can you pick up milk?
Me: [lifts gallon] yea it’s easy
Wife: I mean from the store
Me: I would imagine it weighs the same there too
2:26 AM · Mar 19, 2020·Twitter for Android
 
Reddit—Dadjokes 
Posted by u/rancherrick July 29, 2020
Wife: Can you pick up milk?
Husband: Lifting Gallon yeah
Wife: No, I mean at the store.
Husband: I imagine it would weigh the same there…