“The main ingredient in hand sanitizer is paranoia” is a saying that has been printed on many images.
   
“Nat is a total germophobe. She could single-handedly keep the antibacterialhand-sanitizer companies in business. I stand by my theory that the main ingredient in hand sanitizer is paranoia” is the thought of character Berry Lambert in the novel With a Little Luck (2011) by Caprice Crane. “The main ingredient in hand sanitizer is paranoia” was posted on Twitter by Caprice Crane on February 29, 2012.
       
“The main ingredient in hand sanitizer is paranoia” became a saying of some people in 2020 during the COVID-19 (coronavirus) pandemic.
     
   
Wikipedia: COVID-19 pandemic
The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in December 2019 in Wuhan, China. The outbreak was declared a Public Health Emergency of International Concern in January 2020 and a pandemic in March 2020.
     
Google Books
With a Little Luck:
A Novel
By Caprice Crane
New York, NY: Bantam Books
2011
Pg. 146:
For as much of a slob as she is in her apartment, there’s a difference between being messy and being dirty, and Nat is a total germophobe. She could single-handedly keep the antibacterialhand-sanitizer companies in business. I stand by my theory that the main ingredient in hand sanitizer is paranoia.
   
Twitter
Merrijoy
@Fatty_Magoo
“I stand by my theory that the main ingredient in hand sanitizer is paranoia.” - Berry Lambert
1:27 PM · Jul 29, 2011·Twitter Web Client
   
Twitter
caprice crane
@capricecrane
The main ingredient in hand sanitizer is paranoia.
9:27 PM · Feb 29, 2012·Twitter Web Client
   
Twitter
Sir Walter of Tech
@wpavlik2
How true, I like the scented variety…RT @capricecrane: The main ingredient in hand sanitizer is paranoia.
9:28 PM · Feb 29, 2012·TweetDeck
 
Google Books
Thoughts and Near Thoughts by Jim Harris
By Jim Harris
Victoria, BC: Trafford Publishing
2016
Pg. ?:
July 2, 2014
I have discovered the main ingredient in hand sanitizer is paranoia.
   
Twitter
Humor For The Hopeless
@PatheticLoserAB
The main ingredient in hand sanitizer is paranoia.
2:52 PM · Jul 31, 2019·Twitter Web Client
 
Twitter
Amanda Softstar
@ASoftstar
The main ingredient in hand sanitizer is paranoia.
1:21 PM · Dec 14, 2020·Twitter Web App
 
Twitter
conspiracybot
@conspiracyb0t
The main ingredient in hand sanitizer is paranoia.
3:59 AM · Mar 1, 2021·conspiracyb0t