“Pokertox” (poker + Botox)  was introduced by a New York doctor in 2012. Botox injections to a poker player’s face would stop that player from a facial reaction to the cards.
 
“Pokertox is Botox for poker players (so they can keep a straight face). So is this a performance enhancing drug?” was posted on Twitter by Hoops for Life on November 29, 2012. “Is botox considered a performance enhancing drug for poker players?” was posted on Twitter by Stacey Borg on March 8, 2013. “Botox could be considered a performance enhancing drug for poker players” was posted on Reddit—Showerthoughts on February 22, 2016. “Botox is a performance-enhancing drug for poker players” was posted on Reddit—Showerthoughts on May 23, 2021.
     
         
HuffPost 
Pokertox: Botox For Gambler’s Poker Face
By David Moye
Nov 20, 2012, 09:20 AM EST | Updated Nov 20, 2012
A doctor of aesthetic medicine in New York is taking a gamble that poker players are going to be the next big growth market for botox.
 
Dr. Jack Berdy has just introduced “Pokertox,” a program of Botox and facial fillers designed to enhance a player’s “poker face,” their ability to hide any sign of facial emotion that might tip off other card players on whether they have a good or bad hand.
 
Twitter
Hoops for Life
@HoopsForLife21
Pokertox is Botox for poker players (so they can keep a straight face). So is this a performance enhancing drug?
10:51 PM · Nov 29, 2012·Twitter for iPhone
   
Twitter
Stacey Borg
@DrCurlytek
Is botox considered a performance enhancing drug for poker players?
2:09 AM · Mar 8, 2013·Twitter for Android
   
Twitter
Pigwash
@pigwash_
Is botox considered a performance enhancing drug for poker?
6:10 AM · Jun 13, 2015·Twitter for Android
   
Twitter
Charlotte
@charIottepickle
Is Botox considered a performance enhancing drug for poker? Because I feel like it would be
1:49 PM · Jun 13, 2015·Twitter for iPhone
       
Reddit—Showerthoughts 
Posted by u/Schdbit September 25, 2015
In professional poker, is Botox considered a performance enhancing drug?
Professional poker players seem to have a frozen appearance and wear sunglasses hats etc. Would Botox take it to the next level?
 
Reddit—Showerthoughts
Posted by u/sactomkiii February 22, 2016
Botox could be considered a performance enhancing drug for poker players
 
Twitter
Jay
@Jay_Bulls
Do you think botox is a performance enhancing drug for poker players?
Yes
25%
No
75%
4 votes
·
Final results
9:51 AM · Feb 23, 2016·Twitter for Android
     
Twitter
Troy Osinoff 🕺
@yo
Is Botox considered a performance enhancing drug for poker?
2:12 PM · Mar 19, 2016·Twitter for iPhone
   
Reddit—Showerthoughts
Posted by u/ohgodwhydidIjoin November 6, 2018
Botox is a Performance-Enhancing Drug in Poker
 
Reddit—Showerthoughts
Posted by u/Valtieri May 23, 2021
Botox is a performance-enhancing drug for poker players
 
Reddit—Showerthoughts
Posted by u/shiri24 September 15, 2022
Botox is a performance enhancing drug for poker.